| Serenade | A musical performance for a lover. |
| Serket | Egyptian goddess of healing scorpions. |
| Seshat | Ancient Egyptian goddess of writing. |
| Shaileshwari | Goddess of the mountain, Parvati. |
| Shakuntani | One who is like a bird |
| Shakuntika | A small or young bird |
| Shallan | One who is very flowing |
| Shayera | A noble bird or falcon. |
| Shimari | A sign of great patience. |
| Shobhaa | One who is full of beauty. |
| Shortcake | A sweet, small baked treat. |
| Shrutikirti | Famous for great wisdom. |
| Shuri | A name meaning princess or sun. |
| Shyamolie | A name meaning dark or dusky. |
| Sigridha | A name meaning victory beauty. |
| Sigrisha | A name meaning victory seeker. |
| Silvermist | A light fog with a silvery hue |
| Simhi | A name meaning a lioness or brave |
| Simhika | A mythological lioness character |
| Siren | A creature of enchanting music |
| Sister | A female sibling by birth. |
| Sit | To rest upon the buttocks. |
| Sitarra | A musical stringed instrument. |
| Six | The number after number five. |
| Skadiya | A name meaning winter goddess. |
| Skuld | One of the three Norse fates. |
| Snapdragon | A flower resembling a dragon. |
| Snooki | A nickname meaning small nose. |
| Sofonisba | A noble Carthaginian princess. |
| Sojourner | One who stays for a short time. |
| Soleia | A name meaning light or the sun. |
| Solene | Derived from the Latin word for solemn. |
| Solfege | A method for teaching musical pitch. |
| Solivagant | One who wanders alone by themselves. |
| Solvi | A name meaning to loosen or release. |
| Sonaal | A name meaning golden or precious. |
| Sonata | A composition played on instruments. |
| Sop | A piece of bread dipped in liquid. |
| Sorbet | A frozen dessert made from fruit. |
| Starfire | A brilliant light from the cosmos. |